Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites

The glucocorticoid (GR) and androgen (AR) receptors execute unique functions in vivo, yet have nearly identical DNA binding specificities. To identify mechanisms that facilitate functional diversification among these transcription factor paralogs, we studied them in an equivalent cellular context. A...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Kulik, Marina, Bothe, Melissa, Kibar, Gözde, Fuchs, Alisa, Schöne, Stefanie, Prekovic, Stefan, Mayayo-Peralta, Isabel, Chung, Ho-Ryun, Zwart, Wilbert, Helsen, Christine, Claessens, Frank, Meijsing, Sebastiaan H
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053126/
https://ncbi.nlm.nih.gov/pubmed/33751115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab185
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