Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites

The glucocorticoid (GR) and androgen (AR) receptors execute unique functions in vivo, yet have nearly identical DNA binding specificities. To identify mechanisms that facilitate functional diversification among these transcription factor paralogs, we studied them in an equivalent cellular context. A...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kulik, Marina, Bothe, Melissa, Kibar, Gözde, Fuchs, Alisa, Schöne, Stefanie, Prekovic, Stefan, Mayayo-Peralta, Isabel, Chung, Ho-Ryun, Zwart, Wilbert, Helsen, Christine, Claessens, Frank, Meijsing, Sebastiaan H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053126/
https://ncbi.nlm.nih.gov/pubmed/33751115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab185
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