Molecular mechanisms of cisplatin-induced nephrotoxicity: a balance on the knife edge between renoprotection and tumor toxicity

BACKGROUND: Cisplatin (cis-diamminedichloroplatinum II, CDDP) is one of the most effective chemotherapeutic agents. However, its clinical use is limited due to the severe side effects, including nephrotoxicity and acute kidney injury (AKI) which develop due to renal accumulation and biotransformatio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biomed Sci
Prif Awduron: Volarevic, Vladislav, Djokovic, Bojana, Jankovic, Marina Gazdic, Harrell, C. Randall, Fellabaum, Crissy, Djonov, Valentin, Arsenijevic, Nebojsa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Review
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417243/
https://ncbi.nlm.nih.gov/pubmed/30866950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-019-0518-9
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