Cocultures of human colorectal tumor spheroids with immune cells reveal the therapeutic potential of MICA/B and NKG2A targeting for cancer treatment

BACKGROUND: Immunotherapies still fail to benefit colorectal cancer (CRC) patients. Relevant functional assays aimed at studying these failures and the efficacy of cancer immunotherapy in human are scarce. 3D tumor cultures, called tumor organoids or spheroids, represent interesting models to study...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Immunother Cancer
Main Authors: Courau, Tristan, Bonnereau, Julie, Chicoteau, Justine, Bottois, Hugo, Remark, Romain, Assante Miranda, Laura, Toubert, Antoine, Blery, Mathieu, Aparicio, Thomas, Allez, Matthieu, Le Bourhis, Lionel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417026/
https://ncbi.nlm.nih.gov/pubmed/30871626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0553-9
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker