Yes-associated protein (YAP) mediates adaptive cardiac hypertrophy in response to pressure overload

Cardiovascular disease (CVD) remains the leading cause of death globally, and heart failure is a major component of CVD-related morbidity and mortality. The development of cardiac hypertrophy in response to hemodynamic overload is initially considered to be beneficial; however, this adaptive respons...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Byun, Jaemin, Del Re, Dominic P., Zhai, Peiyong, Ikeda, Shohei, Shirakabe, Akihiro, Mizushima, Wataru, Miyamoto, Shigeki, Brown, Joan H., Sadoshima, Junichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416448/
https://ncbi.nlm.nih.gov/pubmed/30635403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006123
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