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miR-214 is Stretch-Sensitive in Aortic Valve and Inhibits Aortic Valve Calcification
miR-214 has been recently found to be significantly downregulated in calcified human aortic valves (AVs). ER stress, especially the ATF4-mediated pathway, has also been shown to be significantly upregulated in calcific AV disease. Since elevated cyclic stretch is one of the major mechanical stimuli...
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| Publicado no: | Ann Biomed Eng |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6416061/ https://ncbi.nlm.nih.gov/pubmed/30671754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-019-02206-3 |
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