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Long-term treatment with the mTOR inhibitor rapamycin has minor effect on clinical laboratory markers in middle-aged marmosets.

Interventions to extend lifespan and improve health with increasing age would have significant impact on a growing aged population. There are now several pharmaceutical interventions that extend lifespan in laboratory rodent models with rapamycin, an inhibitor of mechanistic target of rapamycin (mTO...

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Detalhes bibliográficos
Publicado no:Am J Primatol
Main Authors: Sills, Aubrey M., Artavia, Joselyn M., DeRosa, Brian D., Ross, Corinna N., Salmon, Adam B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415526/
https://ncbi.nlm.nih.gov/pubmed/30311681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajp.22927
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