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Pharmaceutical inhibition of mTOR in the common marmoset: effect of rapamycin on regulators of proteostasis in a non-human primate

BACKGROUND: Inhibition of mechanistic target of rapamycin (mTOR) has emerged as a viable means to lengthen lifespan and healthspan in mice, although it is still unclear whether these benefits will extend to other mammalian species. We previously reported results from a pilot experiment wherein commo...

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Bibliografski detalji
Izdano u:Pathobiol Aging Age Relat Dis
Glavni autori: Lelegren, Matthew, Liu, Yuhong, Ross, Corinna, Tardif, Suzette, Salmon, Adam B.
Format: Artigo
Jezik:Inglês
Izdano: Co-Action Publishing 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920937/
https://ncbi.nlm.nih.gov/pubmed/27341957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/pba.v6.31793
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