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Column-Free Purification Methods for Recombinant Proteins Using Self-Cleaving Aggregating Tags

Conventional column chromatography processes to purify recombinant proteins are associated with high production costs and slow volumetric throughput at both laboratory and large scale. Non-chromatographic purifications based on selective aggregating tags have the potential to reduce costs with accep...

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Bibliographic Details
Published in:Polymers (Basel)
Main Authors: Fan, Yamin, Miozzi, Jackelyn M., Stimple, Samuel D., Han, Tzu-Chiang, Wood, David W.
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415421/
https://ncbi.nlm.nih.gov/pubmed/30966502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym10050468
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