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Molecular dynamics simulations of Alzheimer Aβ(40) elongation and lateral association
Amyloid-β (Aβ) peptides can elongate in the fibril axis and associate in the lateral direction. We present detailed atomic Aβ models with different in-register intermolecular β-sheet-β-sheet associations. We probe structural stability, conformational dynamics, and association force of Aβ oligomers w...
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| Pubblicato in: | Front Biosci |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6413880/ https://ncbi.nlm.nih.gov/pubmed/18508486 |
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