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Annular Structures as Intermediates in Fibril Formation of Alzheimer Aβ(17–42)
We report all-atom molecular dynamics simulations of annular β-amyloid (17–42) structures, single- and double-layered, in solution. We assess the structural stability and association force of Aβ annular oligomers associated through different interfaces, with a mutated sequence (M35A), and with the o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779724/ https://ncbi.nlm.nih.gov/pubmed/18457440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp711335b |
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