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Molecular Recognition between Aβ-Specific Single-Domain Antibody and Aβ Misfolded Aggregates

Aβ is the toxic amyloid polypeptide responsible for Alzheimer’s disease (AD). Prevention and elimination of the Aβ misfolded aggregates are the promising therapeutic strategies for the AD treatments. Gammabody, the Aβ-Specific Single-domain (VH) antibody, recognizes Aβ aggregates with high affinity...

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Dades bibliogràfiques
Publicat a:Antibodies (Basel)
Autors principals: Zhang, Mingzhen, Zheng, Jie, Nussinov, Ruth, Ma, Buyong
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6640678/
https://ncbi.nlm.nih.gov/pubmed/31544877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antib7030025
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