HDAC9 complex inhibition improves smooth muscle–dependent stenotic vascular disease

Patients with heterozygous missense mutations in the ACTA2 or MYH11 gene are known to exhibit thoracic aortic aneurysm and a risk of early-onset aortic dissection. However, less common phenotypes involving arterial obstruction are also observed, including coronary and cerebrovascular stenotic diseas...

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Udgivet i:JCI Insight
Main Authors: Lino Cardenas, Christian L., Kessinger, Chase W., Chou, Elizabeth, Ghoshhajra, Brian, Yeri, Ashish S., Das, Saumya, Weintraub, Neal L., Malhotra, Rajeev, Jaffer, Farouc A., Lindsay, Mark E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413784/
https://ncbi.nlm.nih.gov/pubmed/30674723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124706
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