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HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype

Aortic calcification is an important independent predictor of future cardiovascular events. We performed a genome-wide association meta-analysis to determine single nucleotide polymorphisms (SNPs) associated with the extent of abdominal (AAC, n = 9,417) or descending thoracic (TAC, n = 8,422) aortic...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Malhotra, Rajeev, Mauer, Andreas C., Cardenas, Christian L. Lino, Guo, Xiuqing, Yao, Jie, Zhang, Xiaoling, Wunderer, Florian, Smith, Albert V., Wong, Quenna, Pechlivanis, Sonali, Hwang, Shih-Jen, Wang, Judy, Lu, Lingyi, Nicholson, Christopher J., Shelton, Georgia, Buswell, Mary D., Barnes, Hanna J., Sigurslid, Haakon H., Slocum, Charles, O’Rourke, Caitlin, Rhee, David K., Bagchi, Aranya, Nigwekar, Sagar U., Buys, Emmanuel S., Campbell, Catherine Y., Harris, Tamara, Budoff, Matthew, Criqui, Michael H., Rotter, Jerome I., Johnson, Andrew D., Song, Ci, Franceschini, Nora, Debette, Stephanie, Hoffmann, Udo, Kälsch, Hagen, Nöthen, Markus M., Sigurdsson, Sigurdur, Freedman, Barry I., Bowden, Donald W., Jöckel, Karl-Heinz, Moebus, Susanne, Erbel, Raimund, Feitosa, Mary F., Gudnason, Vilmundur, Thanassoulis, George, Zapol, Warren M., Lindsay, Mark E., Bloch, Donald B., Post, Wendy S., O’Donnell, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858575/
https://ncbi.nlm.nih.gov/pubmed/31659325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0514-8
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