LRH1-driven transcription factor circuitry for hepatocyte identity: Super-enhancer cistromic analysis

BACKGROUND: The injured liver loses normal function, with concomitant decrease of key identity genes. Super-enhancers contribute to mammalian cell identity. Here, we identified core transcription factors (TFs) that are active in hepatocytes, using genome-wide analysis and hierarchical ordering of su...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EBioMedicine
Main Authors: Joo, Min Sung, Koo, Ja Hyun, Kim, Tae Hyun, Kim, Yun Seok, Kim, Sang Geon
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Research paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413675/
https://ncbi.nlm.nih.gov/pubmed/30638865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.12.056
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