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AMPK Facilitates Nuclear Accumulation of Nrf2 by Phosphorylating at Serine 550

Nrf2 (nuclear factor erythroid 2-related factor 2) is an antioxidant transcription factor. AMP-activated protein kinase (AMPK) functions as a central regulator of cell survival in response to stressful stimuli. Nrf2 should be coordinated with the cell survival pathway controlled by AMPK, but so far...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Joo, Min Sung, Kim, Won Dong, Lee, Ki Young, Kim, Ji Hyun, Koo, Ja Hyun, Kim, Sang Geon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936058/
https://ncbi.nlm.nih.gov/pubmed/27161318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00118-16
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