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Serine phosphorylation of the small phosphoprotein ICAP1 inhibits its nuclear accumulation

Nuclear accumulation of the small phosphoprotein integrin cytoplasmic domain–associated protein-1 (ICAP1) results in recruitment of its binding partner, Krev/Rap1 interaction trapped-1 (KRIT1), to the nucleus. KRIT1 loss is the most common cause of cerebral cavernous malformation, a neurovascular dy...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Su, Valerie L., Simon, Bertrand, Draheim, Kyle M., Calderwood, David A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062153/
https://ncbi.nlm.nih.gov/pubmed/32005669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009794
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