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Serine phosphorylation of the small phosphoprotein ICAP1 inhibits its nuclear accumulation
Nuclear accumulation of the small phosphoprotein integrin cytoplasmic domain–associated protein-1 (ICAP1) results in recruitment of its binding partner, Krev/Rap1 interaction trapped-1 (KRIT1), to the nucleus. KRIT1 loss is the most common cause of cerebral cavernous malformation, a neurovascular dy...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7062153/ https://ncbi.nlm.nih.gov/pubmed/32005669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009794 |
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