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Development and Validation of an Ultra-Performance Liquid Chromatography Method for the Determination of Wedelolactone in Rat Plasma and its Application in a Pharmacokinetic Study

Wedelolactone is a coumarin ether with significant hepatoprotective effects. However, there are few pharmacokinetic studies of wedelolactone, which will affect the studies of its efficacy and potential toxicity. In this study, a selective ultra-performance liquid chromatography (UPLC) method was dev...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Chen, Qing, Wu, Xiaoxue, Gao, Xuemin, Song, Hua, Zhu, Xuan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413069/
https://ncbi.nlm.nih.gov/pubmed/30791539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24040762
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