Determination of donepezil in human plasma using ultra performance liquid chromatography-tandem mass spectrometry

An ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed and validated for the quantification of donepezil in human plasma. Donepezil and donepezil-D4 were extracted from human plasma by liquid-liquid extraction using a mixture of hexane and ethyl acetate...

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Publicat a:Transl Clin Pharmacol
Autors principals: Jeong, Hyeon-Cheol, Park, Jeong-Eun, Hyun, Ji-Yeon, Park, Min-Kyu, Shin, Dong-Seong, Shin, Kwang-Hee
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Clinical Pharmacology and Therapeutics 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989263/
https://ncbi.nlm.nih.gov/pubmed/32055551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2018.26.2.64
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