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Quantification of apixaban in human plasma using ultra performance liquid chromatography coupled with tandem mass spectrometry

Apixaban, an inhibitor of direct factor Xa, is used for the treatment of venous thromboembolic events or prevention of stroke. Unlike many other anticoagulant agents, it does not need periodic monitoring. However, monitoring is still required to determine the risk of bleeding due to overdose or surg...

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Detalhes bibliográficos
Publicado no:Transl Clin Pharmacol
Main Authors: Jeong, Hyeon-Cheol, Kim, Tae-Eun, Shin, Kwang-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Clinical Pharmacology and Therapeutics 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989270/
https://ncbi.nlm.nih.gov/pubmed/32055579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2019.27.1.33
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