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Quantification of apixaban in human plasma using ultra performance liquid chromatography coupled with tandem mass spectrometry

Apixaban, an inhibitor of direct factor Xa, is used for the treatment of venous thromboembolic events or prevention of stroke. Unlike many other anticoagulant agents, it does not need periodic monitoring. However, monitoring is still required to determine the risk of bleeding due to overdose or surg...

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Détails bibliographiques
Publié dans:Transl Clin Pharmacol
Auteurs principaux: Jeong, Hyeon-Cheol, Kim, Tae-Eun, Shin, Kwang-Hee
Format: Artigo
Langue:Inglês
Publié: Korean Society for Clinical Pharmacology and Therapeutics 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989270/
https://ncbi.nlm.nih.gov/pubmed/32055579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2019.27.1.33
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