Increased Cytotoxicity of Herpes Simplex Virus Thymidine Kinase Expression in Human Induced Pluripotent Stem Cells

Human induced pluripotent stem cells (iPSCs) hold enormous promise for regenerative medicine. The major safety concern is the tumorigenicity of transplanted cells derived from iPSCs. A potential solution would be to introduce a suicide gene into iPSCs as a safety switch. The herpes simplex virus typ...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Iwasawa, Chizuru, Tamura, Ryota, Sugiura, Yuki, Suzuki, Sadafumi, Kuzumaki, Naoko, Narita, Minoru, Suematsu, Makoto, Nakamura, Masaya, Yoshida, Kazunari, Toda, Masahiro, Okano, Hideyuki, Miyoshi, Hiroyuki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413063/
https://ncbi.nlm.nih.gov/pubmed/30769780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040810
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