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The Combined Use of Phenothiazines and Statins Strongly Affects Doxorubicin-Resistance, Apoptosis, and Cox-2 Activity in Colon Cancer Cells

Since none of the multidrug resistance (MDR) modulators tested so far found their way into clinic, a novel approach to overcome the MDR of cancer cells has been proposed. The combined use of two MDR modulators of dissimilar mechanisms of action was suggested to benefit from the synergy between them....

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Vydáno v:Int J Mol Sci
Hlavní autoři: Środa-Pomianek, Kamila, Michalak, Krystyna, Palko-Łabuz, Anna, Uryga, Anna, Świątek, Piotr, Majkowski, Michał, Wesołowska, Olga
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412564/
https://ncbi.nlm.nih.gov/pubmed/30813251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040955
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