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The Combined Use of Phenothiazines and Statins Strongly Affects Doxorubicin-Resistance, Apoptosis, and Cox-2 Activity in Colon Cancer Cells

Since none of the multidrug resistance (MDR) modulators tested so far found their way into clinic, a novel approach to overcome the MDR of cancer cells has been proposed. The combined use of two MDR modulators of dissimilar mechanisms of action was suggested to benefit from the synergy between them....

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Środa-Pomianek, Kamila, Michalak, Krystyna, Palko-Łabuz, Anna, Uryga, Anna, Świątek, Piotr, Majkowski, Michał, Wesołowska, Olga
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412564/
https://ncbi.nlm.nih.gov/pubmed/30813251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040955
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