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Organosilicon Compounds, SILA-409 and SILA-421, as Doxorubicin Resistance-Reversing Agents in Human Colon Cancer Cells

Multidrug resistance (MDR) that occurs in cancer cells constitutes one of the major reasons for chemotherapy failure. The main molecular mechanism of MDR is overexpression of protein transporters from the ATP-binding cassette (ABC) superfamily, such as ABCB1 (multidrug resistance protein 1 (MDR1), P...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wesołowska, Olga, Michalak, Krystyna, Błaszczyk, Maria, Molnár, Joseph, Środa-Pomianek, Kamila
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181076/
https://ncbi.nlm.nih.gov/pubmed/32260260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25071654
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