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The Combined Use of Phenothiazines and Statins Strongly Affects Doxorubicin-Resistance, Apoptosis, and Cox-2 Activity in Colon Cancer Cells

Since none of the multidrug resistance (MDR) modulators tested so far found their way into clinic, a novel approach to overcome the MDR of cancer cells has been proposed. The combined use of two MDR modulators of dissimilar mechanisms of action was suggested to benefit from the synergy between them....

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Środa-Pomianek, Kamila, Michalak, Krystyna, Palko-Łabuz, Anna, Uryga, Anna, Świątek, Piotr, Majkowski, Michał, Wesołowska, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412564/
https://ncbi.nlm.nih.gov/pubmed/30813251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040955
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