Determining the effects of DNA sequence on Hel308 helicase translocation along single-stranded DNA using nanopore tweezers

Motor enzymes that process nucleic-acid substrates play vital roles in all aspects of genome replication, expression, and repair. The DNA and RNA nucleobases are known to affect the kinetics of these systems in biologically meaningful ways. Recently, it was shown that DNA bases control the transloca...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Craig, Jonathan M, Laszlo, Andrew H, Nova, Ian C, Brinkerhoff, Henry, Noakes, Matthew T, Baker, Katherine S, Bowman, Jasmine L, Higinbotham, Hugh R, Mount, Jonathan W, Gundlach, Jens H
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412116/
https://ncbi.nlm.nih.gov/pubmed/30649515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz004
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