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Revealing dynamics of helicase translocation on single-stranded DNA using high-resolution nanopore tweezers
Enzymes that operate on DNA or RNA perform the core functions of replication and expression in all of biology. To gain high-resolution access to the detailed mechanistic behavior of these enzymes, we developed single-molecule picometer-resolution nanopore tweezers (SPRNT), a single-molecule techniqu...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692567/ https://ncbi.nlm.nih.gov/pubmed/29078357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711282114 |
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