Determining the effects of DNA sequence on Hel308 helicase translocation along single-stranded DNA using nanopore tweezers

Motor enzymes that process nucleic-acid substrates play vital roles in all aspects of genome replication, expression, and repair. The DNA and RNA nucleobases are known to affect the kinetics of these systems in biologically meaningful ways. Recently, it was shown that DNA bases control the transloca...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Craig, Jonathan M, Laszlo, Andrew H, Nova, Ian C, Brinkerhoff, Henry, Noakes, Matthew T, Baker, Katherine S, Bowman, Jasmine L, Higinbotham, Hugh R, Mount, Jonathan W, Gundlach, Jens H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412116/
https://ncbi.nlm.nih.gov/pubmed/30649515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz004
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