Determining the effects of DNA sequence on Hel308 helicase translocation along single-stranded DNA using nanopore tweezers

Motor enzymes that process nucleic-acid substrates play vital roles in all aspects of genome replication, expression, and repair. The DNA and RNA nucleobases are known to affect the kinetics of these systems in biologically meaningful ways. Recently, it was shown that DNA bases control the transloca...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Craig, Jonathan M, Laszlo, Andrew H, Nova, Ian C, Brinkerhoff, Henry, Noakes, Matthew T, Baker, Katherine S, Bowman, Jasmine L, Higinbotham, Hugh R, Mount, Jonathan W, Gundlach, Jens H
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Nucleic Acid Enzymes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412116/
https://ncbi.nlm.nih.gov/pubmed/30649515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz004
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