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Regulation of Rep helicase unwinding by an auto-inhibitory subdomain

Helicases are biomolecular motors that unwind nucleic acids, and their regulation is essential for proper maintenance of genomic integrity. Escherichia coli Rep helicase, whose primary role is to help restart stalled replication, serves as a model for Superfamily I helicases. The activity of Rep-lik...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Makurath, Monika A, Whitley, Kevin D, Nguyen, Binh, Lohman, Timothy M, Chemla, Yann R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412110/
https://ncbi.nlm.nih.gov/pubmed/30690484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz023
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