Unwinding forward and sliding back: an intermittent unwinding mode of the BLM helicase

There are lines of evidence that the Bloom syndrome helicase, BLM, catalyzes regression of stalled replication forks and disrupts displacement loops (D-loops) formed during homologous recombination (HR). Here we constructed a forked DNA with a 3′ single-stranded gap and a 5′ double-stranded handle t...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Wang, Shuang, Qin, Wei, Li, Jing-Hua, Lu, Ying, Lu, Ke-Yu, Nong, Da-Guan, Dou, Shuo-Xing, Xu, Chun-Hua, Xi, Xu-Guang, Li, Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402530/
https://ncbi.nlm.nih.gov/pubmed/25765643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv209
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