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Unwinding forward and sliding back: an intermittent unwinding mode of the BLM helicase
There are lines of evidence that the Bloom syndrome helicase, BLM, catalyzes regression of stalled replication forks and disrupts displacement loops (D-loops) formed during homologous recombination (HR). Here we constructed a forked DNA with a 3′ single-stranded gap and a 5′ double-stranded handle t...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4402530/ https://ncbi.nlm.nih.gov/pubmed/25765643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv209 |
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