Donor-derived cell-free DNA predicts allograft failure and mortality after lung transplantation

BACKGROUND: Allograft failure is common in lung-transplant recipients and leads to poor outcomes including early death. No reliable clinical tools exist to identify patients at high risk for allograft failure. This study tested the use of donor-derived cell-free DNA (%ddcfDNA) as a sensitive marker...

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Vydáno v:EBioMedicine
Hlavní autoři: Agbor-Enoh, Sean, Wang, Yan, Tunc, Ilker, Jang, Moon Kyoo, Davis, Andrew, De Vlaminck, Iwijn, Luikart, Helen, Shah, Pali D., Timofte, Irina, Brown, Anne W., Marishta, Argit, Bhatti, Kenneth, Gorham, Sasha, Fideli, Ulgen, Wylie, Jennifer, Grimm, David, Goodwin, Natalie, Yang, Yanqin, Patel, Kapil, Zhu, Jun, Iacono, Aldo, Orens, Jonathan B., Nathan, Steven D., Marboe, Charles, Berry, Gerald J., Quake, Stephen R., Khush, Kiran, Valantine, Hannah A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412014/
https://ncbi.nlm.nih.gov/pubmed/30692045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.12.029
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