Donor-derived cell-free DNA predicts allograft failure and mortality after lung transplantation

BACKGROUND: Allograft failure is common in lung-transplant recipients and leads to poor outcomes including early death. No reliable clinical tools exist to identify patients at high risk for allograft failure. This study tested the use of donor-derived cell-free DNA (%ddcfDNA) as a sensitive marker...

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Publicat a:EBioMedicine
Autors principals: Agbor-Enoh, Sean, Wang, Yan, Tunc, Ilker, Jang, Moon Kyoo, Davis, Andrew, De Vlaminck, Iwijn, Luikart, Helen, Shah, Pali D., Timofte, Irina, Brown, Anne W., Marishta, Argit, Bhatti, Kenneth, Gorham, Sasha, Fideli, Ulgen, Wylie, Jennifer, Grimm, David, Goodwin, Natalie, Yang, Yanqin, Patel, Kapil, Zhu, Jun, Iacono, Aldo, Orens, Jonathan B., Nathan, Steven D., Marboe, Charles, Berry, Gerald J., Quake, Stephen R., Khush, Kiran, Valantine, Hannah A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412014/
https://ncbi.nlm.nih.gov/pubmed/30692045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.12.029
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