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Single-stranded DNA library preparation uncovers the origin and diversity of ultrashort cell-free DNA in plasma
Circulating cell-free DNA (cfDNA) is emerging as a powerful monitoring tool in cancer, pregnancy and organ transplantation. Nucleosomal DNA, the predominant form of plasma cfDNA, can be adapted for sequencing via ligation of double-stranded DNA (dsDNA) adapters. dsDNA library preparations, however,...
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| Опубликовано в: : | Sci Rep |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906518/ https://ncbi.nlm.nih.gov/pubmed/27297799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27859 |
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