The Neuronal Overexpression of Gclc in Drosophila melanogaster Induces Life Extension With Longevity-Associated Transcriptomic Changes in the Thorax

Some effects of aging in animals are tissue-specific. In D. melanogaster neuronal overexpression of Gclc increases lifespan and improves certain physiological parameters associated with health benefits such as locomotor activity, circadian rhythmicity, and stress resistance. Our previous transcripto...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Genet
Prif Awduron: Moskalev, Alexey, Guvatova, Zulfiya, Shaposhnikov, Mikhail, Lashmanova, Ekaterina, Proshkina, Ekaterina, Koval, Liubov, Zhavoronkov, Alex, Krasnov, George, Kudryavtseva, Anna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019
Pynciau:
Genetics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411687/
https://ncbi.nlm.nih.gov/pubmed/30891062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00149
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