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Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster

BACKGROUND: The JAK/STAT signaling pathway is involved in many aging-related cellular functions. However, effects of overexpression of genes controlling JAK/STAT signal transduction on longevity of model organisms have not been studied. Here we evaluate the effect of overexpression of the unpaired 1...

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Veröffentlicht in:BMC Syst Biol
Hauptverfasser: Moskalev, Alexey, Proshkina, Ekaterina, Zhavoronkov, Alex, Shaposhnikov, Mikhail
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399815/
https://ncbi.nlm.nih.gov/pubmed/30836998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-019-0687-x
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