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Overexpression of CBS and CSE genes affects lifespan, stress resistance and locomotor activity in Drosophila melanogaster

Recent experimental studies highlighted the role of hydrogen sulfide (H(2)S) in aging and longevity. The cystathionine ß-synthase (CBS) and cystathionine γ-lyase (CSE) are the key enzymes responsible for H(2)S production. Here we investigated the geroprotective effects of CSE and CBS overexpression...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Shaposhnikov, Mikhail, Proshkina, Ekaterina, Koval, Lyubov, Zemskaya, Nadezhda, Zhavoronkov, Alex, Moskalev, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286861/
https://ncbi.nlm.nih.gov/pubmed/30408770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101630
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