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Overexpression of CBS and CSE genes affects lifespan, stress resistance and locomotor activity in Drosophila melanogaster

Recent experimental studies highlighted the role of hydrogen sulfide (H(2)S) in aging and longevity. The cystathionine ß-synthase (CBS) and cystathionine γ-lyase (CSE) are the key enzymes responsible for H(2)S production. Here we investigated the geroprotective effects of CSE and CBS overexpression...

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Vydáno v:Aging (Albany NY)
Hlavní autoři: Shaposhnikov, Mikhail, Proshkina, Ekaterina, Koval, Lyubov, Zemskaya, Nadezhda, Zhavoronkov, Alex, Moskalev, Alexey
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286861/
https://ncbi.nlm.nih.gov/pubmed/30408770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101630
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