The influence of pro-longevity gene Gclc overexpression on the age-dependent changes in Drosophila transcriptome and biological functions

BACKGROUND: Transcriptional changes that contribute to the organism’s longevity and prevent the age-dependent decline of biological functions are not well understood. Here, we overexpressed pro-longevity gene encoding glutamate-cysteine ligase catalytic subunit (Gclc) and analyzed age-dependent chan...

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Vydáno v:BMC Genomics
Hlavní autoři: Moskalev, Alexey, Shaposhnikov, Mikhail, Proshkina, Ekaterina, Belyi, Alexey, Fedintsev, Alexander, Zhikrivetskaya, Svetlana, Guvatova, Zulfiya, Sadritdinova, Asiya, Snezhkina, Anastasia, Krasnov, George, Kudryavtseva, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249042/
https://ncbi.nlm.nih.gov/pubmed/28105938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3356-0
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