Cerebrospinal fluid biomarkers of neurofibrillary tangles and synaptic dysfunction are associated with longitudinal decline in white matter connectivity: A multi-resolution graph analysis

In addition to the development of beta amyloid plaques and neurofibrillary tangles, Alzheimer's disease (AD) involves the loss of connecting structures including degeneration of myelinated axons and synaptic connections. However, the extent to which white matter tracts change longitudinally, pa...

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Veröffentlicht in:Neuroimage Clin
Hauptverfasser: Kim, Won Hwa, Racine, Annie M., Adluru, Nagesh, Hwang, Seong Jae, Blennow, Kaj, Zetterberg, Henrik, Carlsson, Cynthia M., Asthana, Sanjay, Koscik, Rebecca L., Johnson, Sterling C., Bendlin, Barbara B., Singh, Vikas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411581/
https://ncbi.nlm.nih.gov/pubmed/30502079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2018.10.024
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