Association of longitudinal white matter degeneration and cerebrospinal fluid biomarkers of neurodegeneration, inflammation and Alzheimer’s disease in late-middle-aged adults

Alzheimer’s disease (AD) is characterized by substantial neurodegeneration, including both cortical atrophy and loss of underlying white matter fiber tracts. Understanding longitudinal alterations to white matter may provide new insights into trajectories of brain change in both healthy aging and AD...

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Detalhes bibliográficos
Publicado no:Brain Imaging Behav
Main Authors: Racine, Annie M., Merluzzi, Andrew P., Adluru, Nagesh, Norton, Derek, Koscik, Rebecca L., Clark, Lindsay R., Berman, Sara E., Nicholas, Christopher R., Asthana, Sanjay, Alexander, Andrew L., Blennow, Kaj, Zetterberg, Henrik, Kim, Won Hwa, Singh, Vikas, Carlsson, Cynthia M., Bendlin, Barbara B., Johnson, Sterling C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723250/
https://ncbi.nlm.nih.gov/pubmed/28600739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11682-017-9732-9
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