Age-accelerated cognitive decline in asymptomatic adults with CSF β-amyloid

OBJECTIVE: Compare cognitive and hippocampal volume trajectories in asymptomatic middle-aged and older adults with positive CSF markers of β-amyloid (Aβ) or tau to adults without an Alzheimer disease (AD)-associated biomarker profile. METHODS: Three hundred ninety-two adults enrolled in a longitudin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurology
Prif Awduron: Clark, Lindsay R., Berman, Sara E., Norton, Derek, Koscik, Rebecca L., Jonaitis, Erin, Blennow, Kaj, Bendlin, Barbara B., Asthana, Sanjay, Johnson, Sterling C., Zetterberg, Henrik, Carlsson, Cynthia M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Lippincott Williams & Wilkins 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894934/
https://ncbi.nlm.nih.gov/pubmed/29523644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000005291
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