Hypertension and obesity moderate the relationship between beta-amyloid and cognitive decline in midlife

BACKGROUND: This study tested if central obesity, hypertension, or depressive symptoms moderated the relationship between beta-amyloid (Aβ) and longitudinal cognitive performance in late middle-aged adults enriched for Alzheimer’s disease (AD) risk. METHODS: Participants (n=207; ages=40–70; 73% pare...

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Veröffentlicht in:Alzheimers Dement
Hauptverfasser: Clark, Lindsay R., Koscik, Rebecca L., Allison, Samantha L., Berman, Sara E., Norton, Derek, Carlsson, Cynthia M., Betthauser, Tobey, Bendlin, Barbara B., Christian, Bradley T., Chin, Nathanial, Asthana, Sanjay, Johnson, Sterling C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408972/
https://ncbi.nlm.nih.gov/pubmed/30367828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.09.008
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