Hypertension and obesity moderate the relationship between beta-amyloid and cognitive decline in midlife

BACKGROUND: This study tested if central obesity, hypertension, or depressive symptoms moderated the relationship between beta-amyloid (Aβ) and longitudinal cognitive performance in late middle-aged adults enriched for Alzheimer’s disease (AD) risk. METHODS: Participants (n=207; ages=40–70; 73% pare...

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Vydáno v:Alzheimers Dement
Hlavní autoři: Clark, Lindsay R., Koscik, Rebecca L., Allison, Samantha L., Berman, Sara E., Norton, Derek, Carlsson, Cynthia M., Betthauser, Tobey, Bendlin, Barbara B., Christian, Bradley T., Chin, Nathanial, Asthana, Sanjay, Johnson, Sterling C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408972/
https://ncbi.nlm.nih.gov/pubmed/30367828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.09.008
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