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CGK062, a small chemical molecule, inhibits cancer upregulated gene 2-induced oncogenesis through NEK2 and β-catenin

The mechanisms through which cancer-upregulated gene 2 (CUG2), a novel oncogene, affects Wnt/β-catenin signaling, essential for tumorigenesis, are unclear. In this study, we aimed to elucidate some of these mechanisms in A549 lung cancer cells. Under the overexpression of CUG2, the protein levels an...

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Bibliografiske detaljer
Udgivet i:Int J Oncol
Main Authors: Kaowinn, Sirichat, Oh, Sangtaek, Moon, Jeong, Yoo, Ah Young, Kang, Ho Young, Lee, Mi Rim, Kim, Ji Eun, Hwang, Dae Youn, Youn, So Eun, Koh, Sang Seok, Chung, Young-Hwa
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411349/
https://ncbi.nlm.nih.gov/pubmed/30968157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4724
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