CGK062, a small chemical molecule, inhibits cancer upregulated gene 2-induced oncogenesis through NEK2 and β-catenin

The mechanisms through which cancer-upregulated gene 2 (CUG2), a novel oncogene, affects Wnt/β-catenin signaling, essential for tumorigenesis, are unclear. In this study, we aimed to elucidate some of these mechanisms in A549 lung cancer cells. Under the overexpression of CUG2, the protein levels an...

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Publicat a:Int J Oncol
Autors principals: Kaowinn, Sirichat, Oh, Sangtaek, Moon, Jeong, Yoo, Ah Young, Kang, Ho Young, Lee, Mi Rim, Kim, Ji Eun, Hwang, Dae Youn, Youn, So Eun, Koh, Sang Seok, Chung, Young-Hwa
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411349/
https://ncbi.nlm.nih.gov/pubmed/30968157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4724
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