Overexpression of Cancer Upregulated Gene 2 (CUG2) Decreases Spry2 Through c-Cbl, Leading to Activation of EGFR and β-Catenin Signaling

PURPOSE: The mechanism by which cancer upregulated gene 2 (CUG2) overexpression induces cancer stem cell-like phenotypes is not fully understood. Because the increased activity and expression of epidermal growth factor receptor (EGFR) kinase have been reported in A549 cancer cells overexpressing CUG...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Yawut, Natpaphan, Kaewpiboon, Chutima, Budluang, Phatcharaporn, Cho, Il-Rae, Kaowinn, Sirichat, Koh, Sang Seok, Chung, Young-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573319/
https://ncbi.nlm.nih.gov/pubmed/33116878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S271109
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