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Pan-cancer association of a centrosome amplification gene expression signature with genomic alterations and clinical outcome
Centrosome amplification (CA) is a common feature of human tumours and a promising target for cancer therapy. However, CA’s pan-cancer prevalence, molecular role in tumourigenesis and therapeutic value in the clinical setting are still largely unexplored. Here, we used a transcriptomic signature (CA...
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| Publicat a: | PLoS Comput Biol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6411098/ https://ncbi.nlm.nih.gov/pubmed/30856170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006832 |
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