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α4βδ GABA(A) receptors trigger synaptic pruning and reduce dendritic length of female mouse CA3 hippocampal pyramidal cells at puberty
Synaptic pruning during adolescence is critical for optimal cognition. The CA3 hippocampus contains unique spine types and plays a pivotal role in pattern separation and seizure generation, where sex differences exist, but adolescent pruning has only been studied in the male. Thus, for the present s...
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| Veröffentlicht in: | Neuroscience |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6411036/ https://ncbi.nlm.nih.gov/pubmed/30496825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.11.032 |
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