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α4βδ GABA(A) Receptors Reduce Dendritic Spine Density In CA1 Hippocampus And Impair Relearning Ability Of Adolescent Female Mice: Effects Of A GABA Agonist And A Stress Steroid

Synaptic pruning underlies the transition from an immature to an adult CNS through refinements of neuronal circuits. Our recent study indicates that pubertal synaptic pruning is triggered by the inhibition generated by extrasynaptic α4βδ GABA(A) receptors (GABARs) which are increased for 10 d on den...

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書目詳細資料
發表在:Neuroscience
Main Authors: Afroz, Sonia, Shen, Hui, Smith, Sheryl S.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404891/
https://ncbi.nlm.nih.gov/pubmed/28189613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.01.051
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