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α4βδ GABA(A) Receptors Reduce Dendritic Spine Density In CA1 Hippocampus And Impair Relearning Ability Of Adolescent Female Mice: Effects Of A GABA Agonist And A Stress Steroid
Synaptic pruning underlies the transition from an immature to an adult CNS through refinements of neuronal circuits. Our recent study indicates that pubertal synaptic pruning is triggered by the inhibition generated by extrasynaptic α4βδ GABA(A) receptors (GABARs) which are increased for 10 d on den...
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| Veröffentlicht in: | Neuroscience |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5404891/ https://ncbi.nlm.nih.gov/pubmed/28189613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.01.051 |
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