Tissue-specific BMAL1 cistromes reveal that rhythmic transcription is associated with rhythmic enhancer–enhancer interactions

The mammalian circadian clock relies on the transcription factor CLOCK:BMAL1 to coordinate the rhythmic expression of thousands of genes. Consistent with the various biological functions under clock control, rhythmic gene expression is tissue-specific despite an identical clockwork mechanism in ever...

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Udgivet i:Genes Dev
Main Authors: Beytebiere, Joshua R., Trott, Alexandra J., Greenwell, Ben J., Osborne, Collin A., Vitet, Helene, Spence, Jessica, Yoo, Seung-Hee, Chen, Zheng, Takahashi, Joseph S., Ghaffari, Noushin, Menet, Jerome S.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411008/
https://ncbi.nlm.nih.gov/pubmed/30804225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.322198.118
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